Manage real-time protection when tamper protection is enabled in LogMeIn Pro
Windows Tamper Protection prevents apps from changing the built-in Microsoft antivirus settings, including real-time protection. When Tamper Protection is enabled, you cannot manage real-time protection in LogMeIn Pro. You must turn off Tamper Protection on the host first.
Differences between Real-Time Protection and Tamper Protection
Real-time protection is the built-in Windows antivirus solution that comes pre-deployed with Windows. LogMeIn Pro allows you to manage the antivirus software on your hosts, whether it is the built-in solution or a third-party application.
Tamper Protection is another built-in Windows feature that was designed to block third-party software, like LogMeIn Pro, from changing sensitive Windows system settings, such as the host's antivirus settings. When tamper protection is enabled on a Windows host, you cannot use LogMeIn Pro to manage the host's bult-in antivirus software, that is, Windows real-time protection.
Manage a host's antivirus software with Tamper Protection enabled
When a host uses Real-Time Protection as an antivirus solution, you simply don't. When Tamper Protection is enabled, Windows does not allow LogMeIn Pro to enable Real-Time Protection.
However, when a host uses a third-party antivirus software and you want to manage that with LogMeIn Pro, then the Tamper Protection setting of the host is irrelevant. Again, Tamper Protection blocks third-party apps from changing Windows security settings only, but it allows you to change other third-party apps.
About Tamper Protection statuses

green lock - Tamper Protection is enabled on the host. LogMeIn Pro cannot enable real-time protection on that host.
red lock - Tamper Protection is disabled on the host. LogMeIn Pro can manage real-time protection settings on that host.
gray lock - Tamper Protection status is unknown or irrelevant. This means that a third-party antivirus software is installed on the host, therefore Tamper Protection has no effect on the host's antivirus settings.
Note: For those computers that do not have the latest host version installed, Tamper Protection status is always unknown.
